The introduction of a nuclear energy program is a major undertaking with significant implications for many aspects of national infrastructure, ranging from capacity of the power grid, access roads and production facilities, to the involvement of stakeholders and the development of human resources. For new comers countries without nuclear power, even for those who wish to realize substantial expansion of existing nuclear capacity, it can take up to 10-15 years to develop the necessary infrastructure. One of the crucial problems in nuclear energy implementation are human resources needs and educational infrastructure development in this field. No matter what will be the future energy scenario in the Republic of Macedonia, the nuclear educational program is the first step to have HR in the field of nuclear energy. This paper presents the proposed direction for having HR for establishing national infrastructure in nuclear energy program in Macedonia. This includes establishing and developing ofMONEP(Macedonian NEPIO), and the enhancing the capabilities of the national regulatory body in the Republic of Macedonia.